Yesterday I found out that there was a possibility that either (1) I had been dehydrated last week when they drew blood or (2) my kidneys have been damaged and are not working properly. Results of a repeat test came back today and ruled out dehydration as the cause of the high level of creatinine in my blood, along with some other indicators. I will be scheduling an appointment tomorrow with a nephrologist to pursue the kidney damage issue further. At this point, it is unknown whether this condition is being caused by Cinryze and for now I am still infusing every third day per my immunologist’s instructions.
This means that, around hours 58-62, I begin to experience the HAE-related symptoms of nausea-like queasiness and abdominal irritation. Fortunately, these symptoms have not, so far, had time to become acute before the 72 hour mark and, while I am very uncomfortable and cannot sleep, I am determined to go forward with my plans to attend my step-mother’s wedding and visit my grandmother.
In researching kidney damage, I was surprised to find that, although diabetes and high blood pressure are the major causes of kidney disease, kidney damage can also be caused by some things I am either guilty of or suffer from:
- Hypovolemia (low blood volume) due to blood loss (I suffer from Menorrhagia — abnormally heavy and prolonged menstrual period)
- Dehydration from loss of body fluid (vomiting, diarrhea, sweating, fever) (II”m going through peri-menopause with its attendant hot flashes and night sweats – enough said about that!)
- Poor intake of fluids (I’m so guilty of forgetting to drink and eat – more about that below)
Could these three causes combined be the problem? We know dehydration alone is not the problem, but perhaps in combination. Then add Cinryze to the mix and…sigh. I can’t give up Cinryze, but I can’t give up my kidneys, either.
So here’s the scary stuff:
When kidney function decreases, lethargy, weakness, shortness of breath and generalized swelling may occur.
The shortness of breath is because you develop heart rhythm disturbances and I have to admit that my last two forays into the garden left me gasping and dizzy after only 5 minutes. I blamed it on the heat and being out of shape, but I knew to knock off because I wasn’t feeling right. It took about 10 minutes for my heart beat to return to normal.
The generalized weakness can be due to anemia because you’re not making as much bone marrow. If I’ve already got low blood volume (and my blood pressure was very low yesterday) and my red cell count is diminished…I’d say that would be…bloody awful.
As waste products build in the blood, loss of appetite, lethargy, and fatigue become apparent. Well, I can’t even remember to eat and when I do, it’s a struggle to make myself do it. And with low blood volume and anemia, lethargy and fatigue are pretty much de rigueur — and I’ve been de rigueur’d for months.
When you get to the end stage of kidney failure, you get decreased mental function — to the point of coma. Well, I’m not there yet, but dang! I’m not far from total mental confusion!
At least the nephrologist, who has seen my test results, didn’t order me into the hospital — which means my kidneys can’t be at death’s door yet.
So I’m probably going to be off-line more often than on, doing everything I can to turn this situation around. Those who would like to offer prayers, please pray; those who would like to send healing energy, please do. Those who would like to donate a kidney if I should ever need one – start cleaning up those innards and stand by! LOL!
In faerie love and light,